Anyone interested in skincare has likely heard of 'Rejuran' and 'Skin Booster'.
Both Rejuran and Skin Booster treatments are widely known for restoring the skin's fundamental health or giving it a radiant, dewy appearance. Especially among women in their 20s to 50s, the desire for "youthful" and "clear" skin has significantly increased, leading to explosive demand for these procedures.
However, it's difficult to get accurate information just from Instagram reviews or promotional images. Many people want to understand these treatments based on scientific evidence and information recognized by dermatologists.
This article will explore the differences between Rejuran and Skin Booster injections, their scientifically proven effects on the skin, post-treatment changes, and potential side effects. It is based on medical literature and clinical data, aiming to deliver truthful and reliable information. Whether you're considering aesthetic procedures, have already undergone Rejuran or Skin Booster treatments and are curious about the effects, or are planning to try them soon, this article is structured to help. Let's now dive into the scientific mechanisms, differences, and pre-/post-treatment considerations for Rejuran and Skin Boosters.
Why does combining Rejuran with Skin Booster amplify skincare benefits?
Skincare is not just about moisturizing the surface. It includes delivering nutrients deep into the skin and promoting regeneration. Recently, the beauty industry has been paying increasing attention to using Rejuran in combination with skin booster ampoules.
Rejuran contains powerful regenerative ingredients, while Skin Booster ampoules provide intense hydration and moisture. When used together, they can maximize improvements in skin barrier strength, elasticity, and wrinkle reduction.
This synergy is scientifically backed. The main ingredient in Rejuran, Polynucleotide (PN), helps promote cell regeneration and repair skin structure. Meanwhile, Skin Booster ampoules contain hyaluronic acid and various moisturizing agents that help retain hydration within the skin. In essence, while Rejuran restores and strengthens the skin, the Skin Booster ampoule provides hydration to maintain the skin in optimal condition.
Scientific Effects of Rejuran on the Skin
Rejuran is well known for its regenerative properties. Its key ingredient, Polynucleotide (PN), is derived from salmon DNA and helps repair damaged skin cells and reduce inflammation. Through this process, it improves skin elasticity, reduces wrinkles, and supports skin regeneration and recovery.
Cell Regeneration: PN activates fibroblasts in the skin, promoting the production of collagen and elastin, increasing skin density and elasticity.
Strengthening the Skin Barrier: When the skin barrier is damaged, its ability to protect against external factors weakens. Rejuran helps restore the barrier, enhancing resistance to external stimuli.
Antioxidant and Anti-inflammatory Effects: PN reduces damage from free radicals and alleviates inflammation, helping to maintain healthy skin.
Wrinkle Reduction and Elasticity: Rejuran works deep in the skin to smooth out wrinkles, especially fine lines and those around the eyes.
Scientific Effects of Skin Booster Ampoules on the Skin
Skin Booster ampoules offer immediate hydration and typically include ingredients such as hyaluronic acid, ceramides, and panthenol. Their primary function is to replenish moisture deep within the skin and maintain hydration levels.
Deep Hydration: Hyaluronic acid can retain up to 1000 times its weight in water, deeply hydrating the skin.
Preventing Moisture Loss: Ceramides reinforce the skin barrier, preventing water evaporation and keeping skin moist.
Soothing and Anti-inflammatory: Panthenol and niacinamide calm and reduce skin inflammation, making them suitable for sensitive skin.
Creating a Dewy Skin Effect: Skin booster ampoules form a thin moisture barrier on the skin’s surface, instantly creating a dewy, radiant glow that makes the skin look more vibrant and healthy.
Synergistic Effects of Combining Rejuran with Skin Booster Ampoules
When Rejuran is used together with a skin booster ampoule, the results are significantly enhanced compared to using either one alone. The synergy between the two can be summarized as follows:
Rejuran promotes skin cell regeneration, while the skin booster maintains hydration, thereby enhancing overall efficacy.
Together, they strengthen the skin barrier and boost moisture retention.
They help reduce wrinkles and improve elasticity, resulting in healthier skin.
Skin Improvement Synergy Between Rejuran and Aribell PN Skin Booster
The core of effective skincare lies in regeneration and hydration. Especially when using regeneration-focused Rejuran together with a highly moisturizing skin booster ampoule, results such as increased elasticity, wrinkle reduction, and skin barrier reinforcement can be maximized.
The key to achieving this synergy is that the skin booster ampoule must also contain PN (Polynucleotide) at 0.2%. When Rejuran is used in conjunction with a PN-containing skin booster, the combined benefits significantly improve skin health and moisture levels.
However, it’s not enough to simply use both products together—the correct order of application matters. Rejuran should be administered first, followed by the skin booster.
Why? This article explains the science behind using Rejuran and a 0.2% PN ampoule, and the correct method of application for optimal results.
1. Aribell Refresh Ampoule (Contains 2% PN, equivalent to Rejuran)
2. Aribell Aqua PN Skin Booster Ampoule (Contains 0.1% PN)
Rejuran’s Key Role in Skin Regeneration
(Aribell Refresh Ampoule: 2% PN, same as Rejuran)
Rejuran’s main active ingredient is Polynucleotide (PN), derived from salmon DNA, which helps repair tissue and stimulate cell regeneration.
It increases collagen and elastin production, improves wrinkles, enhances elasticity, and strengthens the skin barrier.
As cells become healthier, the skin tone brightens naturally, and skin problems are reduced.
Rejuran works deep in the dermis, thoroughly repairing damage and fundamentally improving skin structure.
The Function of Salmon-Based Essence with 0.1% PN
Skin booster ampoules offer instant hydration and help retain moisture.
Most traditional skin boosters are based on hyaluronic acid, which draws in moisture and enhances hydration.
However, a skin booster ampoule containing 0.1% PN goes beyond simple hydration.
While hyaluronic acid maintains moisture, PN promotes regeneration and reduces inflammation.
Thus, this type of ampoule not only provides hydration but also supports skin regeneration and protection.
< Skin Changes After Using Aribell Refresh + PN Ampoule >
Maximized Skin Regeneration:
Rejuran (2% PN) stimulates collagen and elastin production in the dermis,
while the Skin Booster (0.2% PN) hydrates the epidermis and supports surface-level regeneration.
Enhanced Collagen Production + Hydration:
Collagen synthesis requires a moist environment.
The hyaluronic acid in the Skin Booster keeps the skin hydrated, facilitating collagen production.
Faster Skin Barrier Recovery:
Rejuran may temporarily weaken the barrier during the regeneration process.
The hydrating action of the Skin Booster protects the skin and promotes barrier repair.
Reduced Inflammation & Soothing Effect:
Rejuran works internally to suppress inflammation,
while the Skin Booster immediately soothes the surface, quickly reducing redness and discomfort after treatment.
Rejuran vs. Skin Booster Injection Methods – Manual vs. Device: Which Is Better?
Rejuran and skin booster injections are widely used for restoring skin health.
Both involve injecting active ingredients directly into the skin to address elasticity, hydration, and skin texture.
But the key question remains:
“Which injection method is more suitable?”
There are two methods:
✅ Manual Injection – The doctor injects point-by-point manually.
✅ Injector Device – A multi-needle device automatically delivers the substance at preset dosage and depth.
Although both methods deliver the ingredients into the deeper layers of the skin,
they differ in treatment time, pain level, absorption, consistency, and skin suitability.
Generally, manual injection is considered more painful, while injector devices are more comfortable.
< Choosing the Injection Method Based on Skin Type and Treatment Goals >
Manual Injection is Suitable For:
Individuals with very thin or sensitive skin.
Uneven or delicate areas such as around the eyes, sides of the nose, and lips.
Targeted treatments (e.g., nasolabial folds, forehead depressions).
Injector Device is Suitable For:
Those looking for even nutrient distribution across the entire face.
People who are sensitive to pain or need quick treatment sessions .
Individuals receiving regular maintenance treatments.
Those with weak skin barriers or redness-prone skin.
Hybrid Injection Approach Is Common Today
Large, flat areas like the forehead, cheekbones, and jawline → Use injector device for quick and even coverage
Detailed, curved areas like under the eyes, nose sides, and around the lips → Use manual injection for precision
This combined approach reduces treatment time while maximizing effectiveness and overall satisfaction.
Rejuran and Standard Skin Boosters Work Below the Surface
Rejuran and standard skin boosters do not work only on the surface—they are injected directly into the deeper layers of the skin.
Rejuran, with its PN (Polynucleotide) content, improves the skin’s structure and strengthens the dermal foundation.
Skin boosters, primarily composed of hyaluronic acid, deliver hydration and radiance.
For the skin to become truly healthy, it must be treated from the inside out.
That’s why this direct-injection method is considered one of the most effective ways to achieve fundamental improvements.
※ Pre- and Post-Treatment Guidelines
If you have an important event, schedule treatment at least 7 days in advance to allow for healing.
Avoid alcohol, overexertion, and sauna use before and after the procedure.
Temporarily discontinue stimulating skincare products (e.g., scrubs, retinol).
After treatment, focus on moisturizing and soothing with hydrating or recovery creams.
Always use sunscreen to prevent pigmentation or post-inflammatory dark spots.
Anyone interested in skincare has likely heard of 'Rejuran' and 'Skin Booster'.
Both Rejuran and Skin Booster treatments are widely known for restoring the skin's fundamental health or giving it a radiant, dewy appearance. Especially among women in their 20s to 50s, the desire for "youthful" and "clear" skin has significantly increased, leading to explosive demand for these procedures.
However, it's difficult to get accurate information just from Instagram reviews or promotional images. Many people want to understand these treatments based on scientific evidence and information recognized by dermatologists.
This article will explore the differences between Rejuran and Skin Booster injections, their scientifically proven effects on the skin, post-treatment changes, and potential side effects. It is based on medical literature and clinical data, aiming to deliver truthful and reliable information. Whether you're considering aesthetic procedures, have already undergone Rejuran or Skin Booster treatments and are curious about the effects, or are planning to try them soon, this article is structured to help. Let's now dive into the scientific mechanisms, differences, and pre-/post-treatment considerations for Rejuran and Skin Boosters.
Why does combining Rejuran with Skin Booster amplify skincare benefits?
Skincare is not just about moisturizing the surface. It includes delivering nutrients deep into the skin and promoting regeneration. Recently, the beauty industry has been paying increasing attention to using Rejuran in combination with skin booster ampoules.
Rejuran contains powerful regenerative ingredients, while Skin Booster ampoules provide intense hydration and moisture. When used together, they can maximize improvements in skin barrier strength, elasticity, and wrinkle reduction.
This synergy is scientifically backed. The main ingredient in Rejuran, Polynucleotide (PN), helps promote cell regeneration and repair skin structure. Meanwhile, Skin Booster ampoules contain hyaluronic acid and various moisturizing agents that help retain hydration within the skin. In essence, while Rejuran restores and strengthens the skin, the Skin Booster ampoule provides hydration to maintain the skin in optimal condition.
Scientific Effects of Rejuran on the Skin
Rejuran is well known for its regenerative properties. Its key ingredient, Polynucleotide (PN), is derived from salmon DNA and helps repair damaged skin cells and reduce inflammation. Through this process, it improves skin elasticity, reduces wrinkles, and supports skin regeneration and recovery.
Cell Regeneration: PN activates fibroblasts in the skin, promoting the production of collagen and elastin, increasing skin density and elasticity.
Strengthening the Skin Barrier: When the skin barrier is damaged, its ability to protect against external factors weakens. Rejuran helps restore the barrier, enhancing resistance to external stimuli.
Antioxidant and Anti-inflammatory Effects: PN reduces damage from free radicals and alleviates inflammation, helping to maintain healthy skin.
Wrinkle Reduction and Elasticity: Rejuran works deep in the skin to smooth out wrinkles, especially fine lines and those around the eyes.
Scientific Effects of Skin Booster Ampoules on the Skin
Skin Booster ampoules offer immediate hydration and typically include ingredients such as hyaluronic acid, ceramides, and panthenol. Their primary function is to replenish moisture deep within the skin and maintain hydration levels.
Deep Hydration: Hyaluronic acid can retain up to 1000 times its weight in water, deeply hydrating the skin.
Preventing Moisture Loss: Ceramides reinforce the skin barrier, preventing water evaporation and keeping skin moist.
Soothing and Anti-inflammatory: Panthenol and niacinamide calm and reduce skin inflammation, making them suitable for sensitive skin.
Creating a Dewy Skin Effect: Skin booster ampoules form a thin moisture barrier on the skin’s surface, instantly creating a dewy, radiant glow that makes the skin look more vibrant and healthy.
Synergistic Effects of Combining Rejuran with Skin Booster Ampoules
When Rejuran is used together with a skin booster ampoule, the results are significantly enhanced compared to using either one alone. The synergy between the two can be summarized as follows:
Rejuran promotes skin cell regeneration, while the skin booster maintains hydration, thereby enhancing overall efficacy.
Together, they strengthen the skin barrier and boost moisture retention.
They help reduce wrinkles and improve elasticity, resulting in healthier skin.
Skin Improvement Synergy Between Rejuran and Aribell PN Skin Booster
The core of effective skincare lies in regeneration and hydration. Especially when using regeneration-focused Rejuran together with a highly moisturizing skin booster ampoule, results such as increased elasticity, wrinkle reduction, and skin barrier reinforcement can be maximized.
The key to achieving this synergy is that the skin booster ampoule must also contain PN (Polynucleotide) at 0.2%. When Rejuran is used in conjunction with a PN-containing skin booster, the combined benefits significantly improve skin health and moisture levels.
However, it’s not enough to simply use both products together—the correct order of application matters. Rejuran should be administered first, followed by the skin booster.
Why? This article explains the science behind using Rejuran and a 0.2% PN ampoule, and the correct method of application for optimal results.
1. Aribell Refresh Ampoule (Contains 2% PN, equivalent to Rejuran)
2. Aribell Aqua PN Skin Booster Ampoule (Contains 0.1% PN)
Rejuran’s Key Role in Skin Regeneration
(Aribell Refresh Ampoule: 2% PN, same as Rejuran)
Rejuran’s main active ingredient is Polynucleotide (PN), derived from salmon DNA, which helps repair tissue and stimulate cell regeneration.
It increases collagen and elastin production, improves wrinkles, enhances elasticity, and strengthens the skin barrier.
As cells become healthier, the skin tone brightens naturally, and skin problems are reduced.
Rejuran works deep in the dermis, thoroughly repairing damage and fundamentally improving skin structure.
The Function of Salmon-Based Essence with 0.1% PN
Skin booster ampoules offer instant hydration and help retain moisture.
Most traditional skin boosters are based on hyaluronic acid, which draws in moisture and enhances hydration.
However, a skin booster ampoule containing 0.1% PN goes beyond simple hydration.
While hyaluronic acid maintains moisture, PN promotes regeneration and reduces inflammation.
Thus, this type of ampoule not only provides hydration but also supports skin regeneration and protection.
< Skin Changes After Using Aribell Refresh + PN Ampoule >
Maximized Skin Regeneration:
Rejuran (2% PN) stimulates collagen and elastin production in the dermis,
while the Skin Booster (0.2% PN) hydrates the epidermis and supports surface-level regeneration.
Enhanced Collagen Production + Hydration:
Collagen synthesis requires a moist environment.
The hyaluronic acid in the Skin Booster keeps the skin hydrated, facilitating collagen production.
Faster Skin Barrier Recovery:
Rejuran may temporarily weaken the barrier during the regeneration process.
The hydrating action of the Skin Booster protects the skin and promotes barrier repair.
Reduced Inflammation & Soothing Effect:
Rejuran works internally to suppress inflammation,
while the Skin Booster immediately soothes the surface, quickly reducing redness and discomfort after treatment.
Rejuran vs. Skin Booster Injection Methods – Manual vs. Device: Which Is Better?
Rejuran and skin booster injections are widely used for restoring skin health.
Both involve injecting active ingredients directly into the skin to address elasticity, hydration, and skin texture.
But the key question remains:
“Which injection method is more suitable?”
There are two methods:
✅ Manual Injection – The doctor injects point-by-point manually.
✅ Injector Device – A multi-needle device automatically delivers the substance at preset dosage and depth.
Although both methods deliver the ingredients into the deeper layers of the skin,
they differ in treatment time, pain level, absorption, consistency, and skin suitability.
Generally, manual injection is considered more painful, while injector devices are more comfortable.
< Choosing the Injection Method Based on Skin Type and Treatment Goals >
Manual Injection is Suitable For:
Individuals with very thin or sensitive skin.
Uneven or delicate areas such as around the eyes, sides of the nose, and lips.
Targeted treatments (e.g., nasolabial folds, forehead depressions).
Injector Device is Suitable For:
Those looking for even nutrient distribution across the entire face.
People who are sensitive to pain or need quick treatment sessions .
Individuals receiving regular maintenance treatments.
Those with weak skin barriers or redness-prone skin.
Hybrid Injection Approach Is Common Today
Large, flat areas like the forehead, cheekbones, and jawline → Use injector device for quick and even coverage
Detailed, curved areas like under the eyes, nose sides, and around the lips → Use manual injection for precision
This combined approach reduces treatment time while maximizing effectiveness and overall satisfaction.
Rejuran and Standard Skin Boosters Work Below the Surface
Rejuran and standard skin boosters do not work only on the surface—they are injected directly into the deeper layers of the skin.
Rejuran, with its PN (Polynucleotide) content, improves the skin’s structure and strengthens the dermal foundation.
Skin boosters, primarily composed of hyaluronic acid, deliver hydration and radiance.
For the skin to become truly healthy, it must be treated from the inside out.
That’s why this direct-injection method is considered one of the most effective ways to achieve fundamental improvements.
※ Pre- and Post-Treatment Guidelines
If you have an important event, schedule treatment at least 7 days in advance to allow for healing.
Avoid alcohol, overexertion, and sauna use before and after the procedure.
Temporarily discontinue stimulating skincare products (e.g., scrubs, retinol).
After treatment, focus on moisturizing and soothing with hydrating or recovery creams.
Always use sunscreen to prevent pigmentation or post-inflammatory dark spots.